Ciclesonide (CAS No.: 126544-47-6 or 141845-82-1)
Keywords:
Bile acids, prednisolone derivatives, and epiandrosterone derivatives
Category:
| Basic Information | |
| English name: | ciclesonide |
| Specifications | greater than or equal to 9 8.5% |
| Chemical properties | |
| Molecular formula: | C32H44O7 |
| Molecular weight: | 540.6876 |
| Density | 1.23g/cm3 |
| Melting point | 202–209 degree C |
| Boiling point | 665 degree C at 760 mmHg |
| Flash point | 210 degree C |
| Purity: | greater than or equal to 9 8.5% |
| Vapor pressure | 1.61E-20 mmHg at 25 degree C |
| Quality Standards | |
| Appearance | White powder |
| Identification (infrared) | Match with the reference standard |
| Content (HPLC) | greater than or equal to 9 8.5% |
| Usage Instructions | |
| Ciclesonide is a novel inhaled glucocorticoid for the treatment of asthma, classified as an adrenocortical hormone. Other drugs in this class include beclomethasone dipropionate, budesonide, and fluticasone propionate. This product is administered in an inactive form. | |
| Nature of the hazard | |
| Ciclesonide (Ciclesonide) It takes effect more quickly than budesonide, and its systemic side effects are lower than those of budesonide and fluticasone propionate, even at high doses. 160 mu g Moreover, the degree of plasma cortisol suppression is higher than that with other inhaled corticosteroids (higher plasma cortisol levels are associated with greater systemic side effects). The comparative table of local adverse effects is as follows: Adverse effects: this product, fluticasone propionate, budesonide Difficulty in producing voice (hoarseness) 1.6% 4% – 8% 1% – 6% Sore throat 1.9% 10% – 14% 5% – 10% Thrush 0.2% 2% – 5% 2% – 4% | |
| Storage | |
| Store in a sealed, dry place. | |
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